Town boss Mick McCarthy has made his promised changes with strike pair Daryl Murphy and Freddie Sears amongst those dropping to the bench.
Chris Wood and ex-Leeds striker Luke Varney are handed their full Blues debuts with Paul Anderson and Jonny Parr starting on the right and left of midfield respectively and Kevin Bru and Richard Chaplow amongst the subs.
Cameron Stewart - who was on loan with the Whites last season - and Paddy Kenny, a former Leeds keeper, Kundai Benyu and Alex Henshall also made the trip but are left out of the 18. Ex-Whites striker Noel Hunt, who is on crutches and expected to be out for the season due to his medial knee ligament injury, was also amongst those to travel.
Leeds: Silvestri, Wootton, Bamba, Bellusci, Cooper, Byram, Cook, Murphy, Mowatt, C Taylor, Sharp. Subs: S Taylor, Berardi, Sloth, Doukara, Antenucci, Cani, Morison.
Town: Bialkowski, Chambers (c), Mings, Berra, Smith, Skuse, Tabb, Anderson, Parr, Varney, Wood. Subs: Gerken, Clarke, Chaplow, Connolly, Bru, Sears, Murphy. Referee: Mark Brown (East Yorkshire).