Teddy Bishop is out of Saturday’s game away against Championship leaders Watford and Jonny Parr is a doubt, while David McGoldrick, Luke Hyam, Dean Gerken and Darren Ambrose again all miss out.
McCarthy confirmed that none of those who have missed the last few games will be ready to make their return at Vicarage Road.
"No is the answer to that, not at all,” he said. "In fact we’ve got possibly two more missing. Jonny Parr got a kick and he hasn’t trained today, so he’s a doubt.
"And Teddy Bishop won’t play as he’s got sore shins, sort of the onset of shin splints, which is the last thing we want. The pitches have gone from really heavy to being quite firm.
"He came off [on Tuesday], he got a kick on them as well and he won’t be involved on Saturday.
"He will be a top player Bish, I don’t doubt that, but we’ve got to be careful with him. The last thing I need is for him to be suffering with shin splints and missing the rest of the season because if that does become worse that’s what could happen. But we’re not going to let it happen.”
McCarthy says no decision has yet been made on whether Bishop will be left out of the England U19s squad, the 18-year-old having received a first international call earlier in the week.
"I don’t know,” he added. "I’m going to speak to [England U19s coach] Sean O’Driscoll first.
"To be called up for England at any level should be an honour, certainly. It’s sad if he can’t go but I’ve got to give them the medical report first.”
McCarthy hopes Hyam, who has been suffering with a knee injury, McGoldrick, who has had a thigh problem, and Ambrose could return after the international break.
"I hope so,” McCarthy continued. "Luke was out training today. They had to go and introduce me to him because I haven’t seen him for so long.
"He had a smile on his face, he was out on the grass, out in the fresh air and out of the gym. I think he’s far more optimistic.
"Didz, I just don’t know. He’s not been troubled by it too much but he is being troubled by it enough so he can’t train.”
He says McGoldrick won’t go away with the Republic of Ireland next week, having initially been named in Martin O’Neill’s provisional squad.
"He’s not fit, I haven’t got him down on my desk as being in the preliminary squad because they know he’s injured,” the Town boss said.
"Darren Ambrose must be ruing the fact that he trained that day and he pulled up with his hamstring. That’s been really long-term injury.”
Keeper Gerken will again be left out having been knocked unconscious during last week’s game at Middlesbrough.
"He’s not involved because we’ve got one game and then we’ve got two weeks before the next one so what’s the point of taking any risk?” McCarthy added. "No a chance. He’s fine, but I’m not going to risk him.”
The Blues manager says there are currently no loan additions on the horizon with the deadline a week today: "Not at the moment, nothing’s happening.”