Right-back Josh Emmanuel, 17, makes his senior debut as the Blues take on Brentford in their season opener at Griffin Park. Jonas Knudsen, Ryan Fraser and Ainsley Maitland-Niles all make their Town debuts.
Dane Knudsen lines up at left-back with skipper Luke Chambers joining Tommy Smith in the centre of the defence with Christophe Berra banned for one game for his play-off red card at the end of last season. Jonny Parr is out with a thigh injury, while Teddy Bishop has also picked up a knock.
Fraser will be on the left and Maitland-Niles on the right with Kevin Bru joining Cole Skuse in the centre.
Freddie Sears starts up front alongside Daryl Murphy with David McGoldrick and Brett Pitman on the bench.
Brentford: Button, McCormack, Dean, Tarkowkski, Bidwell, Diagouraga, Kerschbaumer, Gogia, Jota, Judge, Hofmann. Subs: Bonham, Bjelland, Gray, Vibe, O'Connell, Yennaris, Barbet.
Town: Bialkowski, Emmanuel, Chambers (c), Smith, Knudsen, Skuse, Bru, Fraser, Maitland-Niles, Sears, Murphy. Subs: Gerken, Yorwerth, Coke, Douglas, Touré, Pitman, McGoldrick. Referee: David Coote (Nottinghamshire).