Town boss Mick McCarthy has made two changes to the team which started last week’s opening Championship game at Brentford with Christophe Berra and Jonathan Douglas replacing youngster Josh Emmanuel, who drops to the bench, and the injured Kevin Bru.
Berra will be in his usual position at the centre of the defence with skipper Luke Chambers moving to right-back.
Left-back Jonas Knudsen and winger Ainsley Maitland-Niles make their home debuts for the Blues, while Douglas makes his first league start. Former Wednesday midfielder Giles Coke is on the bench.
Town: Bialkowski, Chambers (c), Knudsen, Berra, Smith, Skuse, Douglas, Maitland-Niles, Fraser, Murphy, Sears. Subs: Gerken, McGoldrick, Pitman, Coke, Tabb, Emmanuel, Touré.
Sheffield Wednesday: Westwood, Hunt, Helan, Lees, Loovens (c), Hutchinson, Matias, McGugan, Lopez, Wallace, Joao. Subs: Wildsmith, Palmer, Semedo, Nuhiu, Lee, Sasso, Sougou. Referee: James Linington (Newport Isle-of-Wight).