Town centre-half Christophe Berra is facing four weeks out having suffered a hamstring injury in training earlier in the week, manager Mick McCarthy has confirmed.
"Christophe Berra is missing, as he was the other night [at Doncaster]. He was down to play for half a game along with Tommy Smith but he did his hamstring on Monday, so it’s going to be about four weeks before he’s back,” McCarthy said.
"We’ll look at whether he'll miss the games after the international break. Thankfully the break is coming at the right time for all of us who have had six games already and are making it seven on Saturday.
"It’s strange for Christophe, it’s the first time he’s ever had one, it’s a real surprise. But he will miss Saturday and he probably will miss the first game back.”
Josh Emmanuel looks set to be at right-back with skipper Luke Chambers moving into the centre alongside Tommy Smith. New addition Piotr Malarczyk’s signing won’t be completed in time for him to be involved.
Striker Daryl Murphy (calf) and midfielders Kevin Bru and Teddy Bishop (both hamstring) are also sidelined until after the international break, while Jonny Parr is not yet ready to return to the squad after his thigh problem and Luke Hyam is a long-term absentee having undergone knee surgery in the summer.
Keeper Bartosz Bialkowski is back with the squad having been in Poland following his father’s death last weekend and McCarthy confirmed that he would be in the squad and considered for selection.
Berra and Murphy are both ruled out of international action with Scotland and the Republic of Ireland respectively.