Janoi Donacien and Wes Burns return to the Blues XI facing Luton Town at Colchester United’s Jobserve Community Stadium (KO 7pm).
Donacien, who was brought up in Luton and was a schoolboy with the Hatters, had been suffering with a minor tendon problem, while Burns picked up a calf knock in Austria.
Christian Walton is in goal with Donacien on the right of the back four with Leif Davis on the left and Luke Woolfenden and Cameron Burgess the centre-halves.
Skipper Sam Morsy is in central midfield with Jack Taylor, while behind striker George Hirst, Burns is on the right, Conor Chaplin is in the middle and Nathan Broadhead is on the left of the three.
Harry Clarke (tendon) and Cameron Humphreys (concussion) are again absent along with Massimo Luongo, who came off with a tight groin at Cambridge.
Luton include three of their new signings, Mads Andersen, one-time Town trialist Chiedozie Ogbene and Tahith Chong.
Town: Walton, Donacien, Woolfenden, Burgess, Burns, Morsy (c), Taylor, Davis, Chaplin, Broadhead, Hirst. Subs: Baggott, Edmundson, Evans, Ladapo, Harness, Ball, Jackson, Hutchinson, Leigh, Edwards, Hladky, Carr, Aluko, Slicker.
Luton: Shea, Adebayo, Andersen, Berry, Chong, Clark, Doughty, Lockyer, Morris, Ogbene, Potts. Subs: Macey, Francis, Campbell, Watson, Woodrow, McAtee, Taylor, Johnson, Nelson, Luker, Odell-Bature. Referee: Gavin Ward (Surrey).