Axel Tuanzebe makes a surprise return to the Blues’ XI as Town take on Spurs in their first competitive game at the Tottenham Hotspur Stadium.
The DR Congo international, who last month underwent surgery due to severe cut to his hand, comes in at right-back with Ben Johnson moving to the right-sided role ahead of him.
Omari Hutchinson looks set to switch to the middle with Conor Chaplin dropping to the bench.
In Town’s only other change Jens Cajuste comes into midfield for the suspended Kalvin Phillips.
Former Tottenham pair Massimo Luongo and Jack Clarke are on the bench, along with Harry Clarke, back from suspension, with Nathan Broadhead dropping out of the 20.
Spurs name the same team which beat Aston Villa 4-1 a week ago with central defender Cristian Romero OK despite missing the 3-2 Europa League defeat away against Galatasaray on Thursday due to a toe injury.
Tottenham: Vicario, Pedro Porro, Romero, Dragusin, Udogie; Bentancur, Sarr, Kulusevski; Johnson, Solanke, Son (c). Subs: Forster, Spence, Davies, Gray, Bissouma, Bergvall, Maddison, Werner, Lankshear.
Town: Muric, Tuanzebe, O'Shea, Burgess, Davis, Morsy (c), Cajuste, Johnson, Hutchinson, Szmodics, Delap. Subs: Walton, H Clarke, Woolfenden, Townsend, Luongo, Burns, J Clarke, Chaplin, Hirst. Referee: Darren England (Doncaster). VAR official: John Brooks.