| Very interesting data around the mutation of Covid as well 08:20 - Nov 26 with 516 views | homer_123 |
The D614G variant mutation spread more quickly and easily within the population.
In part, this explains why it has spread far more rapidly within Europe as opposed to Asia. D614 is becoming less prevalent in the wild now and it is the G variant.
The G variant was noted back in January as the spread of the virus moved outside of Asia, more widely, to Europe and beyond.
Studies have been out for a while on this since Aug/ Sept but I'm not sure how widely reported and discussed it has been. We've seen reported the Mink strain of the virus recently and also the Spanish variant as well. Absolutely fascinating (from a science perspective) in terms of how these mutate but also, what a challenge it presents in terms of vaccines and their long term effectiveness.
Recent data suggests that, several components of immune memory of SARS-CoV-2 tended to persist for at least 6 months - which is good (notably B cells - these bad boys jumpy start the anti-body response), for example.
Over in Kenya, some interesting data suggests pre-existing exposure to SARS-CoV-2 - which may account for the Kenya's low death rate compared with infection rates. By July Spain had seen 28,000 deaths....Kenya, just under 350.
Link: https://science.sciencemag.org/content/early/2020/11/11/science.abe1916
One of the most interesting findings I've seen talked about this month is with Children....
"Scientists have found antibodies that recognize SARS-CoV-2 in the blood of people who have never caught the virus. Children are particularly likely to harbour such antibodies, which might explain why most infected children have either mild illness or none at all."
Link: https://science.sciencemag.org/content/early/2020/11/05/science.abe1107 [Post edited 26 Nov 2020 8:34]
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| Very interesting data around the mutation of Covid as well on 08:27 - Nov 26 with 474 views | StokieBlue |
Can you link the source for the existing immunity in children and Kenya please.
SB |  | | |
| Very interesting data around the mutation of Covid as well on 09:22 - Nov 26 with 405 views | StokieBlue |
Thanks.
The abstract for that first paper is basically a list of caveats:
"The spread of SARS-CoV-2 in Africa is poorly described."
"However, the extent of SARS-CoV-2 exposure in the community remains unknown."
" Population-weighted, test-performance-adjusted national seroprevalence was 4.3%"
So it's very interesting and some more research should be done but the abstract basically says we don't have data and maybe 5% of people have antibodies which isn't a huge amount at all. It's also only a subset of the population - blood donors.
I'll try and give it a proper read through later. Certainly it's true that the known cases of C19 in Kenya and other African countries has been lowered (with a few exceptions like SA).
SB | | | |
| Very interesting data around the mutation of Covid as well on 09:25 - Nov 26 with 394 views | homer_123 |
| Very interesting data around the mutation of Covid as well on 09:22 - Nov 26 by StokieBlue |
Thanks.
The abstract for that first paper is basically a list of caveats:
"The spread of SARS-CoV-2 in Africa is poorly described."
"However, the extent of SARS-CoV-2 exposure in the community remains unknown."
" Population-weighted, test-performance-adjusted national seroprevalence was 4.3%"
So it's very interesting and some more research should be done but the abstract basically says we don't have data and maybe 5% of people have antibodies which isn't a huge amount at all. It's also only a subset of the population - blood donors.
I'll try and give it a proper read through later. Certainly it's true that the known cases of C19 in Kenya and other African countries has been lowered (with a few exceptions like SA).
SB |
Indeed, which is why I used the words 'suggest' and 'may' in relation to the Kenya data.
It's certainly interesting - more research would indeed be worthwhile, though I can only imagine the challenges of doing that within African populations. | |
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| Very interesting data around the mutation of Covid as well on 09:41 - Nov 26 with 379 views | Swansea_Blue |
Heard on t'radio yesterday that apparently Covid-19 has been found in tissue samples collected in Italy back in september 2019. That'll shake up what we think we know about the early transmission if it's true. I bet the Chinese are watching with interest! |  |
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| Very interesting data around the mutation of Covid as well on 09:46 - Nov 26 with 367 views | StokieBlue |
| Very interesting data around the mutation of Covid as well on 09:41 - Nov 26 by Swansea_Blue |
Heard on t'radio yesterday that apparently Covid-19 has been found in tissue samples collected in Italy back in september 2019. That'll shake up what we think we know about the early transmission if it's true. I bet the Chinese are watching with interest! |
It's certainly possible it's been around for longer than we suspect.
I read an article months ago suggesting that rural Chinese had some immunity because they had seen it before. However it wasn't peer reviewed and I've heard nothing else about it since.
Perhaps it was circulating and doing nothing and then mutated to make it worse. However even if it was it would have been in very small numbers as the vast majority of people don't have any antibodies.
SB | | | |
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