| Oxford United 5 v 0 Leyton Orient Papa John's Trophy Tuesday, 30th August 2022 Kick-off 19:45 |  |
Head to Head - Oxford United v Leyton Orient
| HOME | AWAY | TOTAL | ||||||||||||||||
| Competition | P | W | D | L | F | A | W | D | L | F | A | W | D | L | F | A | ||
| Sky Bet Championship | 12 | 0 | 0 | 0 | 0 | 0 | 2 | 7 | 3 | 12 | 13 | 2 | 7 | 3 | 12 | 13 | ||
| Sky Bet League One | 10 | 0 | 0 | 0 | 0 | 0 | 4 | 2 | 4 | 17 | 17 | 4 | 2 | 4 | 17 | 17 | ||
| EL4 | 8 | 0 | 0 | 0 | 0 | 0 | 2 | 4 | 2 | 11 | 11 | 2 | 4 | 2 | 11 | 11 | ||
| All League | 30 | 0 | 0 | 0 | 0 | 0 | 8 | 13 | 9 | 40 | 41 | 8 | 13 | 9 | 40 | 41 | ||
| EFL Trophy | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 6 | 0 | 0 | 2 | 0 | 6 | ||
| Football League Div 3 | 6 | 0 | 0 | 0 | 0 | 0 | 2 | 1 | 3 | 6 | 8 | 2 | 1 | 3 | 6 | 8 | ||
| Total: | 38 | 0 | 0 | 0 | 0 | 0 | 10 | 14 | 14 | 46 | 55 | 10 | 14 | 14 | 46 | 55 | ||
| Average goals scored: | 1.211 | ||||||
| Average goals conceded: | 1.447 | ||||||
| Win with greatest margin: | 4 |
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| Loss with greatest margin: | 5 |
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| Most goals in a match: | 7 |
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| 24 Feb 2024 | Sky Bet League One | Oxford United | 1-2 | Leyton Orient | W | |
| 11 Nov 2023 | Sky Bet League One | Leyton Orient | 2-3 | Oxford United | W | |
| 30 Aug 2022 | EFL Trophy | Oxford United | 5-0 | Leyton Orient | L | |
| 12 Mar 2016 | EL4 | Oxford United | 0-1 | Leyton Orient | W | |
| 17 Oct 2015 | EL4 | Leyton Orient | 2-2 | Oxford United | D | |
| 6 May 2006 | EL4 | Oxford United | 2-3 | Leyton Orient | W | |
| 23 Nov 2005 | EFL Trophy | Oxford United | 1-0 | Leyton Orient | L | |
| 29 Oct 2005 | EL4 | Leyton Orient | 1-0 | Oxford United | L | |
| 28 Mar 2005 | EL4 | Oxford United | 2-2 | Leyton Orient | D | |
| 21 Aug 2004 | EL4 | Leyton Orient | 0-0 | Oxford United | D | |
| 7 Feb 2004 | Football League Div 3 | Leyton Orient | 1-0 | Oxford United | L | |
| 26 Dec 2003 | Football League Div 3 | Oxford United | 2-1 | Leyton Orient | L | |
| 4 Mar 2003 | Football League Div 3 | Oxford United | 0-2 | Leyton Orient | W | |
| 17 Sep 2002 | Football League Div 3 | Leyton Orient | 1-2 | Oxford United | W | |
| 6 Apr 2002 | Football League Div 3 | Oxford United | 1-1 | Leyton Orient | D | |
| 20 Nov 2001 | Football League Div 3 | Leyton Orient | 3-0 | Oxford United | L | |
| 4 Mar 1995 | EL4 | Leyton Orient | 1 - 1 | Oxford United | D | |
| 24 Sep 1994 | EL4 | Oxford United | 3 - 2 | Leyton Orient | L | |
| 7 May 1984 | EL3 | Leyton Orient | 1 - 2 | Oxford United | W | |
| 31 Dec 1983 | EL3 | Oxford United | 5 - 2 | Leyton Orient | L | |
| 9 Apr 1983 | EL3 | Oxford United | 2 - 2 | Leyton Orient | D | |
| 4 Dec 1982 | EL3 | Leyton Orient | 1 - 5 | Oxford United | W | |
| 24 Apr 1976 | League Division Two | Leyton Orient | 2 - 1 | Oxford United | L | |
| 4 Oct 1975 | League Division Two | Oxford United | 2 - 1 | Leyton Orient | L | |
| 31 Mar 1975 | League Division Two | Leyton Orient | 1 - 1 | Oxford United | D | |
| 21 Sep 1974 | League Division Two | Oxford United | 1 - 2 | Leyton Orient | W | |
| 10 Mar 1974 | League Division Two | Leyton Orient | 1 - 1 | Oxford United | D | |
| 27 Oct 1973 | League Division Two | Oxford United | 1 - 1 | Leyton Orient | D | |
| 17 Feb 1973 | League Division Two | Oxford United | 2 - 1 | Leyton Orient | L | |
| 12 Aug 1972 | League Division Two | Leyton Orient | 1 - 1 | Oxford United | D | |
| 16 Oct 1971 | League Division Two | Leyton Orient | 1 - 1 | Oxford United | D | |
| 14 Aug 1971 | League Division Two | Oxford United | 1 - 1 | Leyton Orient | D | |
| 10 Apr 1971 | League Division Two | Leyton Orient | 0 - 0 | Oxford United | D | |
| 10 Mar 1971 | League Division Two | Oxford United | 0 - 1 | Leyton Orient | W | |
| 13 Apr 1968 | EL3 | Leyton Orient | 1 - 0 | Oxford United | L | |
| 18 Nov 1967 | EL3 | Oxford United | 2 - 0 | Leyton Orient | L | |
| 27 Mar 1967 | EL3 | Leyton Orient | 2 - 1 | Oxford United | L | |
| 24 Mar 1967 | EL3 | Oxford United | 0 - 0 | Leyton Orient | D |