Forum | New gene therapy for children with leukaemia by StokieBlue

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New gene therapy for children with leukaemia 10:31 - Dec 13 with 455 views

This is a great story and hopefully a treatment which will go on to benefit many people going forward.

https://www.theguardian.com/science/2022/dec/11/revolutionary-gene-therapy-offer

Alyssa had T-cell leukaemia, chemotherapy and a bone marrow transplant didn't work. Given this they decided to treat her with base-edited T-Cells (T-Cells where the DNA has been modified) from a donor which were designed to hunt out and kill only the leukaemia causing T-Cells.

She's now been in remission for 6 months and is doing well and given the T-Cells can come from any donor and then modified it's looking like a very promising treatment for which will be able to be offered to children earlier when they are less sick and could cover other types of leukaemia.

If anyone wants a more scientific explanation than the Guardian article you can get that here:

https://www.news-medical.net/news/20221212/GOSH-delivers-world-first-base-edited

SB

SB - (not Simon Batford)

New gene therapy for children with leukaemia on 20:33 - Dec 13 with 368 views

Nthsuffolkblue

Saw something on this a couple of days ago. Brilliant news.

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